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It was recently found that the cytoplasmic butyryl-coenzyme A (butyryl-CoA) dehydrogenase-EtfAB complex from Clostridium kluyveri couples the exergonic reduction of crotonyl-CoA to butyryl-CoA with NADH and the endergonic reduction of ferredoxin with NADH via flavin-based electron bifurcation. We report here on a second cytoplasmic enzyme complex in C. kluyveri capable of energetic coupling
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Get PriceCellular interaction is inevitable in the pathomechanism of human disease. Formation of heterotypic cellular aggregates, between distinct cells of hematopoietic and nonhematopoietic origin, may be involved in events leading to inflammation and the complex process of cancer progression. Among adhesion receptors, the family of selectins with their ligands have been considered as one of the major
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Get PriceGroundwater ecosystems deliver services that are vital to human well-being and environmental quality. Overexploitation of groundwater threatens biodiversity and ecosystem stability worldwide, underscoring the need to discover, describe, and sustain groundwater-dependent species before they are lost. Here we present a phylogenomic analysis of a salamander radiation endemic to the karstic
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